IVD reagent abu Alamar zuciya

Cardiac Troponin I (cTnI) wani nau'i ne na dangin troponin wanda aka fi amfani dashi azaman alamar lahani na zuciya.Cardiac troponin I na musamman ne don nama na zuciya kuma ana gano shi a cikin jini kawai idan rauni na myocardial ya faru.Saboda cardiac troponin I yana da matukar damuwa da ƙayyadaddun alamar ƙwayar zuciya (myocardium), ana iya amfani da matakan jini don taimakawa wajen bambanta tsakanin angina marar tsayayye da ciwon zuciya (ciwon zuciya) a cikin mutanen da ke fama da ciwon kirji ko ciwo mai tsanani.

Ana amfani da isoform na zuciya na TnT ko'ina azaman alamar rauni na ƙwayar zuciya, kamar yadda cTnI yake.cTnT yana da motsi iri ɗaya na sakin jiki a cikin jini da kuma hankali ɗaya don ƙananan rauni na zuciya kamar cTnI.A cikin jinin marasa lafiya na myocardial infarction (AMI), yawanci ana samun cTnT a cikin kyauta yayin da cTnI galibi ana samunsa a cikin hadaddun tare da TnC.

Troponin C, wanda kuma aka sani da TN-C ko TnC, furotin ne wanda ke zaune a cikin hadaddun troponin akan actin bakin ciki filaments na tsoka mai rauni (zuciya, kwarangwal mai sauri, ko jinkirin skeletal) kuma yana da alhakin ɗaure calcium don kunnawa. raunin tsoka.Troponin C an ɓoye shi ta hanyar ƙwayar TNNC1 a cikin mutane don duka ƙwayar zuciya da jinkirin kwarangwal.

myoglobin furotin ne na cytoplasmic wanda ke ɗaure oxygen akan ƙungiyar heme.Yana ɗaukar rukunin globulin guda ɗaya kawai, yayin da haemoglobin yana da guda huɗu.Ko da yake ƙungiyar heme ta yi kama da waɗanda ke cikin Hb, Mb tana da kusanci ga iskar oxygen fiye da haemoglobin.Wannan bambanci yana da alaƙa da rawarsa daban-daban: yayin da haemoglobin ke jigilar iskar oxygen, aikin myoglobin shine adana iskar oxygen.

Ana amfani da Digoxin don magance gazawar zuciya, yawanci tare da wasu magunguna.Hakanan ana amfani dashi don magance wasu nau'ikan bugun bugun zuciya na rashin daidaituwa (kamar fibrillation na yau da kullun).Yin maganin gazawar zuciya na iya taimakawa wajen kiyaye ikon tafiya da motsa jiki kuma yana iya inganta ƙarfin zuciyar ku.Yin maganin bugun zuciya mara ka'ida kuma zai iya inganta ikon motsa jiki.Digoxin na cikin rukunin magunguna da ake kira cardiac glycosides.Yana aiki ta hanyar shafar wasu ma'adanai (sodium da potassium) a cikin ƙwayoyin zuciya.Wannan yana rage damuwa a kan zuciya kuma yana taimaka mata ta kiyaye al'ada, tsayayye, da ƙarfin bugun zuciya.

CK-MB a cikin myocardial infarction (AMI), da CK-BB a cikin lalacewar kwakwalwa da kuma mummunan ciwon ƙwayar hanji.Ana auna CK-MB ko dai ta hanyar aikin enzyme ko taro mai yawa kuma ana auna shi azaman alamar ba kawai a cikin ganewar asali na AMI ba har ma a cikin AMI da ake zargi da kuma angina maras tabbas.

Nau'in-zuciya-Fatty-Acid-Binding-Protein (hFABP) furotin ne, wanda ke da hannu a cikin jigilar mycardial na intracellular (Bruins Slot et al., 2010; Reiter et al., 2013).Bayan myocardial necrosis hFABP da aka saki da sauri cikin jini kuma saboda haka an bincika a matsayin biomarker ga AMI.Koyaya, saboda ƙarancin hankali da ƙayyadaddun hFABP ba a tabbatar da amfani ba, idan aka kwatanta da aikin bincike na hs-Tn assays (Bruins Slot et al., 2010; Reiter et al., 2013).

Lipoprotein-Associated Phospholipase A2(Lp-PLA2)

Lipids sune kitse a cikin jinin ku.Lipoproteins sune hadewar kitse da sunadaran da ke dauke da kitse a cikin jinin ku.Idan kuna da Lp-PLA2 a cikin jinin ku, kuna iya samun kitse mai yawa a cikin arteries ɗinku waɗanda ke cikin haɗarin fashewa da haifar da cututtukan zuciya ko bugun jini.

D-dimer (ko D dimer) samfur ne na lalata fibrin (ko FDP), ƙaramin furotin da ke cikin jini bayan zubar jini ya lalace ta hanyar fibrinolysis.Sunan haka ne saboda yana ƙunshe da gutsuttsuran D guda biyu na furotin fibrin wanda aka haɗa ta hanyar haɗin giciye.